A healthy heart is so strong that it is almost never a cause of tiredness during exercise. Tiredness during exercise comes from your muscles. They run out of fuel or out of oxygen. Skeletal muscles use both fat and sugar for energy. When your muscles run out of their stored sugar supply, called glycogen, they cannot contract and function adequately. You feel tired, your muscles hurt and you have difficulty coordinating them. On the other hand, your heart muscle gets energy directly from fat and sugar in your blood and even from a breakdown product of metabolism called lactic acid. It is virtually impossible for the heart muscle to run out of fuel unless you are starving to death.A healthy heart doesn't run out of oxygen either. Oxygen comes...