Why Migraines May Reduce Breast Cancer Risk

Few migraine sufferers can see any bright side to their pain, but now we have one study showing that a history of migraines is associated with a lower risk for breast cancer. The report appears in Cancer Epidemiology, Biomarkers & Prevention (November 2008). Researchers pooled data from two studies of postmenopausal women to compare odds ratios among 1900 with breast cancer and 1400 controls. Women who had migraines showed reduced risks for ductal and lobular carcinomas, especially hormone-receptor–positive tumors.

One of the triggers for migraines is a sudden drop in estrogen that causes a drop in brain levels of serotonin, the neurotransmitter that makes you happy and smart. Premenstrual syndrome occurs when the sudden drop in estrogen in the later part of the menstrual cycle causes a drop in serotonin that can make some women sad and depressed. Women who suffer migraines may have lower levels of estrogen, the female hormone that can stimulate breast cancers to grow.