There is good data to show that women with low as well as high blood levels of the male hormone, testosterone, also are at increased risk for depression. One recent study shows that women who have blood levels of free testosterone below 0.4 ng/ml are at high risk for depression, as well as osteoporosis, lack of interest in making love, and an increase in total body fat. Like men, women suffer a progressive lowering of their blood levels of testosterone with a drop by 50 percent from age 20 to menopause at age 52. After menopause, a woman's levels of testosterone remain fairly constant over the years. Within 24 hours of having her ovaries removed, a woman's blood levels of testosterone drop by more than 70 percent. Just taking birth control pills markedly lower a woman's blood levels of testosterone because the estrogen in birth control pills shuts down the brain that produces FSH the hormone that causes the ovaries to produce testosterone.
High levels of testosterone also increase a woman's risk for depression. Women who have high levels of male hormones also often have excess hair on their faces and bodies, acne, loss of air on the top of their heads, lots of fat in their bellies, and cysts on their ovaries. These women also are at increased risk for being very aggressive. Higher male hormone levels are seen in women before and after giving birth, and may be responsible for post-partum depression. It has also been reported that depression in girls before they reach puberty and start menstruating is associated with an increase in male hormones.
Testosterone replacement therapy in women with low blood levels of that hormone, has been reported to protect them from getting fat. If you are a woman who suffers from depression, ask your doctor to draw blood levels of thyroid hormones called T3, T4 and TSH; and male hormones called testosterone and DHEAS. If your thyroid hormones are abnormal, you should be taking both thyroid hormones called T3 and T4. If your testosterone level is low, you may need that hormone. If it is too high, you probably have polycystic ovary syndrome ; you need to restrict bakery products, pastas, and sugar and take Glucophage to lower blood sugar levels. If your testosterone is low, you may need testosterone replacement. Journal reference; more on antidepressants